An age-defying nighttime moisturizer that intensively addresses lines and wrinkles before they become more serious. Offers visible reduction in the appearance of wrinkles and helps promote silky smooth skin condition while encouraging recovery by morning. Newly reformulated, Shiseido Benefiance Wrinkle Resist 24 targets every step of wrinkle formation for youthful looking skin that can resist signs of aging. 50 ml Available at Madison Avenue and Beverly Hills. Shiseido Women's Benefiance Wrinkle Resist 24 Night Cream A great designer gift. Shop Shiseido at Barneys New York.